Insomnia Clinical Trial

It is reported that in the United States there are 70 million people suffer from Insomnia (insufficient sleep) to put that into perspective there are 323 million population in the USA at the time of writing this article. So roughly 22% of people in the USA do not get enough sleep, this in turn can lead to serious medical problems.

Obviously it is far from ideal taking sleeping pills. They can help you to get enough sleep but can also have substantial negative side effects. CBD is a terrific natural remedy, speaking from experience I know it works well in terms of getting enough sleep and a high quality sleep. You wake up in the morning feeling refreshed and not feeling groggy.
Unfortunately there have not been enough clinical trials in relation to CBD, THC or a combination of both of these Cannabinoids on various medical conditions. Even though Insomnia affects so many people there simply have not been many clinical trials on how CBD effects sleep in humans or in rodents.

So lets take a step back and consider how CBD could be beneficial for those with a sleep disorder. CBD is considered to be a phytocannabinoid (Plant derived natural product capable of either directly interacting with cannabinoid receptors or sharing chemical similarity with cannabinoids or both). To put this into simple terms CBD is a natural chemical which influences the brain by interacting with the brain’s cannabinoid receptors called the endocannabinoid system.

So the technical definition for endocannabinoid system (ECS) is a follows: A group of cannabinoid receptors found in the human brain and through the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. It is known as the body’s own cannabinoid system which regulates a variety of physiological processes including appetite, pain, mood, movement, memory, sleep and controlling the psychoactive effects of cannabis.
CBD acts in a very interesting way it tends to make you feel energized and alert. It activates the same adenosine receptors as caffeine, a stimulant. However when it come time to sleep it can assist by making your mind feel relaxed and this enables you to fall asleep. CBD’s anxiolytic (anxiety-inhibiting) properties help make you feel calm which is essential for sleep. It appears that CBD does not directly regulate sleep. At the end of the day many people find by taking CBD an hour or two before going to bed can really help them get a good nights sleep.
Also relating to sleep, somnolence, a state of feeling drowsy or sleepy, has been reported with CBD consumption. While the onset of somnolence may help humans sleep.

Summary of Insomnia CBD Clinical Trials

While the basis for this CBD-and-sleep theory is largely made in rodent studies, some research has been done on sleep-impaired but otherwise healthy humans.

In a 1981 Brazilian study, researchers at the Escola Paulista de Medicina in São Paulo assigned 15 insomniacs to a CBD dose (ranging between 40 mg and 160 mg), placebo, or Nitrazepam, a hypnotic drug indicated for relief from anxiety and insomnia. With the highest CBD dose, sleep significantly increased, although dream recall was reduced, compared to placebo. The reduction of dream recall is presumably due to a reduction of REM sleep, wherein dreams are most active. However you may find that you still have good dream recall if you take CBD and many people have positive dreams.
You may like to read the in depth review on the clinical trials of Sativex which is a cannabis spray (2.7 mg of THC and 2.5 mg of CBD). This trial was set up to learn how Sativex effected pain and sleep.